down syndrome and consanguinity

نویسندگان

amir akhavan rezayat

mohammad hassanzadeh nazarabadi

mohammad sobhan sheikh andalibi

hossein mohaddes ardabili

چکیده

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Parental consanguinity and the Majewski syndrome.

We report a female infant with the Majewski syndrome, one of a group of conditions characterised by short ribs, polydactyly, dwarfism, and early neonatal death. This syndrome seems to be extremely rare, with only five well documented cases reported and, including this case, nine recorded in all. The Majewski syndrome is considered to be recessively inherited, and this report adds further suppor...

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Stigma in Iranian Down Syndrome

Objectives: Stigma is a negative value. Many behaviors are to ward Stigmatized people. Down syndrome is one of conditions with Stigma. The aim of this study is to determine the sources of labeling in iranian Down syndrome. Methods: The View of 105 Down syndrome families concerning stigma were conducted. All of Down syndrome was under 50 years. Results: A fair proportion of Down syndrome f...

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Sensation Seeking and Social SkillsinChildren with Autism Disorderand Down-Syndrome

Objective: The present study was carried out to study the relationship between sensation seeking and social skills in two groups of school age patients Down-Syndrome (DS) and Autism Disorder (DS).  Methods: This is a descriptive-analytic and correlation study in which all participants were of primary school age (10 to 13 years) with Down-Syndrome and Autism Disorder of autism spectrum disord...

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Down Syndrome: Current Status, Challenges and Future Perspectives

Down syndrome (DS) is a birth defect with huge medical and social costs, caused by trisomy of whole or part of chromosome 21. It is the most prevalent genetic disease worldwide and the common genetic cause of intellectual disabilities appearing in about 1 in 400-1500 newborns. Although the syndrome had been described thousands of years before, it was named after John Langdon Down who described ...

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DNA-Repair Capacity in Down\'s Syndrome

Down's syndrome (DS) is the most common chromosomal abnormality in human. Subjects with DS are known to be peridisposed to develop leukemia. The molecular basis of the association between DS and leukemia is unknown. The unscheduled DNA synthesis (UDS) test measure the ability of DNA-repair in mammalian cells after excision of a stretch of DNA containing the region of damage induced by chemical ...

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Down syndrome (DS) is associated with many neurological complications including cognitive deficits, early-onset dementia -which resembles Alzheimer’s diseaseand seizures. Although seizures and epilepsy were not mentioned in the original description of DS (Down, 1866) the prevalence of seizures in individuals with DS is now known to be higher than in the general population, but lower than in pat...

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عنوان ژورنال:
journal of research in medical sciences

جلد ۱۸، شماره ۱۱، صفحات ۰-۰

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